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In general, the application of a mechanistically orientated drug classification system would result in a consistent and sufficient classification logic, where drugs and drug classes appear only once within the classification system (Alvano and Zieher 2020

Exploring synergistic interactions between flavonoids and these drug classes could reveal novel therapeutic strategies with improved efficacy

1 Introduction Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, with a global prevalence of approximately 10%13%